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Symbol
Name
ID

Zic1
zinc finger protein of the cerebellum 1
MGI:106683

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Posterior fossa cyst at the fourth ventricle

Microcephaly

Ectopic posterior pituitary

Optic nerve hypoplasia

Dilated fourth ventricle

Hydrocephalus

Partial agenesis of the corpus callosum

Agenesis of cerebellar vermis

Partial absence of cerebellar vermis

Chiari type I malformation

Truncal ataxia

Cranial nerve paralysis

Increased intracranial pressure

Delayed speech and language development

Autism

Diminished ability to concentrate

Intellectual disability

Obstructive sleep apnea

Headache

Global developmental delay

Mild global developmental delay

Seizure

Disease(s) Associated with ZIC1

craniosynostosis

Dandy-Walker syndrome

Mouse Phenotypes		abnormal cerebellum development	abnormal cerebellar foliation	reduced cerebellar foliation	abnormal cerebellum vermis morphology	cerebellum vermis hypoplasia	cerebellum hypoplasia
Availability	Mouse Genotype	abnormal cerebellum development	abnormal cerebellar foliation	reduced cerebellar foliation	abnormal cerebellum vermis morphology	cerebellum vermis hypoplasia	cerebellum hypoplasia
	Zic1^tm1Jaru/Zic1^tm1Jaru
	Zic1/Zic4^tm1Kjmi/Zic1⁺
	Zic1^tm1Jaru/Zic1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23